Antoine Dufour, PhD

Assistant Professor, University of Calgary

Department of Physiology & Pharmacology

The goal of my lab is to understand how proteolytic post-translational modifications lead to the activation or inactivation of immune responses in inflammatory diseases. By the irreversible processing of bioactive proteins and signaling molecules, proteases modulate all aspects of biology. We focus on proteases and their substrates on a cell, tissue, or organism-wide scale.

Dr. Antoine Dufour is an Assistant Professor in the Department of Physiology and Pharmacology at the University of Calgary. Dr. Dufour obtained his BA (Hons.) in Chemistry from the State University of New York (SUNY) at Oswego, his MSc and PhD in Chemical Biology from the Stony Brook University (2010). He completed a Postdoctoral Fellowship in Biochemistry at the University of British Columbia in 2017 under the supervision of Dr. Chris Overall. Antoine’s research is focused on the role of proteases in immunity and novel drug target identification in inflammatory musculoskeletal diseases, with a particular interest in quantitative mass spectrometry and systems biology. He owns two patents for the inhibitory methods of protease-mediated cell migration. His research program aims to understand the key mechanisms of inflammatory and immune responses in human diseases. Antoine has already published over 70  journal papers, 4 book chapters, and has an outstanding track record of academic awards. Most recently, Dr. Dufour was named as one of Calgary’s Top 40 Under 40 in 2020, was awarded the 2021 Young Investigator Award from the Canadian Society for Mass Spectrometry and the Groll Calpain award in 2022.

Welcome to our lab and feel free to contact us if you want to learn more, or even better, join our team!